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phenobarbital will lessen the level or impact of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Strong or average CYP3A4 inducers might improve fee of diazepam elimination; consequently, efficacy of diazepam could be lowered.Barbiturates are metabolized primarily with the hepatic microsomal enzyme progr

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